Researchers speculate that Type 2 diabetes is caused by a combination of environmental and genetic factors, although specific causal factors are unknown. Now an international team of scientists has found four points on the human gene map that together account for 70 per cent of the genetic predisposition to type 2 diabetes.
They identified four different areas of genetic variation that conferred a significant risk of developing diabetes and confirmed that a fifth area, a gene called TCF7L2 suspected in diabetes, is associated with the disease.
“Our new findings mean that we can create a good genetic test to predict people’s risk of developing this type of diabetes,” said Philippe Froguel of Imperial College London, who worked on the study.
The discovery is remarkable and will certainly be a great benefit in years to come, helping identify those with significant risk factors beyond the obvious.